Israel and Iran have opened a new chapter in their long history of conflict. Israel launched a major attack with strikes early Friday that set off explosions in the Iranian capital of Tehran.

The IDF says Iran has launched about 100 drones towards its territory and says it killed Revolutionary Guards commander Hossein Salami in overnight strikes.

Shapiro served as Deputy Assistant Secretary of Defense for the Middle East until January—charged with, among other things, considering scenarios in which tensions between Israel and Iran escalated into all-out war and preparing U.

American citizens in Israel are strongly advised to limit internal travel and to maintain a high level of situational awareness. Iran remains under a longstanding "Level 4: Do Not Travel" advisory due to risks of terrorism, kidnapping, wrongful detention, and civil unrest.

Our main focus today we'll be on the major overnight air strikes launched by Israel against a large number of targets in Iran.

The military strikes jolted investors, raising concerns that a broader Mideast conflict would disrupt the world’s energy supplies.

Ben Rhodes, former deputy national security advisor, talks with Jen Psaki about the awkwardness of the Trump administration trying to distance itself from Israel's attack on Iran, and what it means about Donald Trump's status that Israel's attack came while Trump was attempting to negotiate a new nuclear deal with Iran.