The San Francisco 49ers were absolutely ravaged by injuries last season, which played a massive role in their disappointing 6 ...

Kyle Shanahan shared an update on Mac Jones after the San Francisco 49ers quarterback sustained a knee injury against the Las ...

The 49ers are contemplating placing Givens on IR to start the year. Shanahan said the team has several decisions to make on ...

The NFL has finally realized that it doesn't make sense to provide smelling salts to players who may be using them to mask ...

The San Francisco 49ers' Super Bowl hangover has been replaced by youth-fueled enthusiasm. But a bevy of injuries has head ...

Head coach Kyle Shanahan provided updates on QB Mac Jones, OL Dominick Puni, and others, discussed looming 53-man roster decisions, and shared his outlook on the team's energy heading into Week 1.

The 49ers face injury concerns as Mac Jones targets Week 1 return as Brock Purdy’s reliable backup quarterback option.

The 49ers will likely have several players on injured lists after cut-down day, with receiver Brandon Aiyuk (knee) and safety Malik Mustapha (knee) expected to miss at least the first four games on ...

San Francisco 49ers coach Kyle Shanahan didn't use offensive tackle Trent Williams in their joint practice with the Las Vegas ...

The San Francisco 49ers reportedly make a flurry of roster moves ahead of their preseason finale against the Los Angeles ...

Former Detroit Lions quarterback Nate Sudfeld signed with the San Francisco 49ers and will view for the chance to back up Brock Purdy.

The San Francisco 49ers saw three players go down with injuries on Saturday. Here's what Kyle Shanahan said after the game.