Pittsburgh Pirates (29-42, fifth in the NL Central) vs. Chicago Cubs (42-28, first in the NL Central) Chicago; Saturday, 1:20 p.m. CDT PITCHING PROBABLES: Pirates: Mike Burrows (1-1, 5.00 ERA, 1.39 WHIP,

The Pittsburgh Pirates defeated the Chicago Cubs 2-1 in 10 innings on Friday afternoon at Wrigley Field. Paul Skenes took a no-decision after throwing 5.0-shutout innings and Isiah Kiner-Falefa drove in the game-winning run on a sac fly in the top of the 10th.

The Pittsburgh Pirates changed their lineup ahead of their next game vs. the Chicago Cubs, who bring in a left-handed pitcher. Cubs will have left-handed pitcher Matthew Boyd make the start vs. the Pirates at Wrigley Field,

Pittsburgh Pirates right-hander Paul Skenes is no stranger to impressive accomplishments. On Friday, he made the wrong kind of history with his start against the Chicago Cubs ( box score ).

The Pittsburgh Pirates (29-42) visit the Chicago Cubs (42-28) Saturday for the third game of their 4-game series. First pitch from Wrigley Field is at 2:20 p.m. ET. Let's analyze BetMGM Sportsbook's MLB odds around the Pirates vs. Cubs odds and make our expert MLB picks and predictions for the best bets.

The Pittsburgh Pirates had strong pitching performances, including from rookie right-handed starting pitcher Mike Burrows, but the offense failed i

SportsLine's model simulated Paul Skenes and the Pittsburgh Pirates vs. Chicago Cubs 10,000 times and revealed its MLB picks for Friday afternoon's matchup at Wrigley Field in Chicago

Rookie Cade Horton matched Pittsburgh Pirates ace Paul Skenes in a pitchers’ duel Friday, but the Chicago Cubs lost 2-1 in 10 innings.

Pirates ace Paul Skenes struck out five in five scoreless innings. Skenes was matched by Cade Horton, who permitted three hits in 5 2/3 shutout innings.