UConn Center on Aging researchers have published a new editorial in the journal Aging titled "Polyploidy-induced senescence: Linking development, differentiation, repair, and (possibly) cancer?" In ...

Researchers profiled mitochondrial circular RNAs in human blood cells and found age-related depletion of circMT-RNR2, linked to mitochondrial metabolism and senescence. The RNA-binding protein GRSF1 ...

A new editorial was published in Volume 18 of Aging-US on February 8, 2026, titled "Polyploidy-induced senescence: Linking development, differentiation, repair, and (possibly) cancer?" In this ...

Aging cells secrete substances known to promote the growth of cancer cells. The development of drugs that can selectively kill these cells or inhibit the secretion of substances is ongoing. The latest ...

Researchers have identified a biological mechanism that helps explain why some lung and ovarian cancers become resistant to ...

T cell senescence occurs in the TME, affecting cancer prognosis and immunotherapy efficacy. The TME induces T cell senescence through multiple pathways, including persistent stimulation by ...

Explore the risks of postpartum cancer and discover how cellular senescence affects breast tissue after pregnancy.

Postpartum breast cancer is diagnosed five to ten years after giving birth. It is associated with a higher risk of metastasis and a lower survival rate compared with women who have not been pregnant ...

Cellular senescence—an irreversible cell-cycle arrest coupled with the production of pro-inflammatory secretions known as SASP—is now viewed as a central driver of musculoskeletal aging. Accumulation ...

A wearable light therapy device tuned to near-infrared wavelengths has reduced a key cellular aging marker by 92% in laboratory tests on human hair follicle cells, according to new research. The ...