A UCLA study found that macrophages rely on interferon gamma signaling from past infections to preserve innate defenses.

Cytokines play a central role in regulating physiological processes, largely because of their ability to orchestrate intercellular communication. As ...

Cells have sophisticated methods of sensing stimuli and communicating with nearby cells in response to these stimuli. For example, macrophages can sense environmental stimuli—tissue damage, foreign ...

The Interleukin-1 Receptor-Like 2 (IL-1RL2) cytokine can promote inflammatory diseases and have a role in controlling infection. The receptor can recognize multiple agonists and has been implicated in ...

Microglial cells, the primary immune cells of the brain and central nervous system, are known to undergo striking morphological changes in response to sensory or neural stimuli. However, the ...

Researchers provide essential insights on the molecular activation of the MAP kinase p38?, the final switch triggering the inflammatory response. Inflammation is a cellular coping mechanism when ...

Rheumatoid arthritis (RA) is a common autoimmune disease in which the immune system recognizes autoantigens on otherwise healthy joint tissues as foreign invaders, inducing a localized inflammatory ...

Cytokines and their kin, alternatively called interleukins, growth factors, interferons, necrosis factors, and others, are soluble messengers responsible for communication between nearby cells, ...

Many proteins and peptides affect the growth, identity, and function of eukaryotic cells. Very often their effects are highly pleiotropic, making exact boundaries and distinctions between proteins ...

SOUTH SAN FRANCISCO, Calif.--(BUSINESS WIRE)--CERo Therapeutics, Inc., a biopharmaceutical company pioneering the development of novel autologous engineered immune cell therapies, today presented the ...