HIV-seq identifies key differences in HIV-infected cells before and after starting antiretroviral therapy to support treatment research.

The tiny shell protecting the HIV virus resembles a slightly rounded ice cream cone, but there is nothing sweet about it.

Long-acting antiviral medications are transforming HIV prevention and care, requiring only minimalistic dosing. But as the use of lenacapavir expands, scientists are probing a critical question: If ...

The rate of HIV infection continues to climb globally. Around 40 million people live with HIV-1, the most common HIV strain. While symptoms can now be better managed with lifelong treatment, there is ...

On the left is integrase in its “intasome” structure of four identical four-part complexes (pink) that connect to create one 16-part complex that locks around viral DNA (blue). On the right is ...

Godfrey Dzhivhuho has dedicated his career to understanding HIV and other infectious diseases, inspired by the epidemic he witnessed growing up. Raised in Warrenton-Kimberly, South Africa, the oldest ...

I see that ViroLogic now offers information on the replicative capacity of patient virus, alongside information on its genotypic and phenotypic resistance profile. How should we use this information ...

CD8 T lymphocytes from immunologically stable HIV-1-infected secrete a soluble factor — termed CAF —, which suppresses HIV-1 replication, but the exact identity of CAF has been unclear. In September ...

University of Delaware professor Juan Perilla (right), is co-author of a new paper that reveals a previously unknown structural role for integrase, a key HIV protein, earlier in the virus' life cycle ...