In this interview, News-Medical Life Science talks to Professor Toshio Ando about his interest in high-speed AFM and how it can revolutionize the observation of protein molecules. How did your ...
Advancements in electronics, miniaturization of cantilevers, and improvement in piezoelectric scanner design have contributed to the continuous development of high-speed atomic force microscopy ...
An enzyme type noted in several cancers is the family of adenosine deaminases acting on RNA (ADARs). These enzymes convert adenosines in double-stranded RNA (dsRNA) into inosines, which cells read as ...
The predicted orientation of the Cas9 protein on the AFM substrate is shown, and a simulated AFM image calculated in the scanning view perspective shows remarkable agreement with previous HS-AFM ...
Scientists at the Nano Life Science Institute (WPI-NanoLSI), Kanazawa University, have captured real-time images showing how a key brain enzyme organizes itself to help memory formation. Their study, ...
High-speed atomic force microscopy (HS-AFM) movies have contributed significantly to our understanding of biomolecular dynamics, because these experiments have resolved conformational changes at ...
(Nanowerk News) Allowing the direct observation of biomolecules in dynamic action, high-speed AFM has opened a new avenue to dynamic structural biology. An enormous amount of successful applications ...
New imaging reveals cancer-linked ADAR1 enzyme structure, potentially enabling targeted therapies by combining HS-AFM and 3D modeling techniques. (Nanowerk News) An enzyme type noted in several ...
Researchers report how high-speed atomic force microscopy can be used for studying DNA wrapping processes. The technique enables visualizing the dynamics of DNA-protein interactions, which in certain ...
Researchers have used high-speed microscopy to investigate native structure and conformational dynamics of hemagglutinin in influenza A. The influenza A viruses, which have instigated deadly pandemics ...
An intrinsic limitation in AFM imaging is that only the surface topography can be acquired, and the AFM tip is too large to resolve details below the nanometer scale. To facilitate the interpretation ...
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