In new research, scientists at the Department of Energy's SLAC National Accelerator Laboratory, in collaboration with ...

Unique approach targets IL-18 with a smaller, IL-18 fusion protein antagonist, with potential for more effective distribution to inflamed tissues than traditional monoclonal antibodies EVO301 has ...

Prostate cancer is one of the most common cancers and the second leading cause of cancer-related death in men worldwide. However, the mechanisms controlling the early stages of prostate cancer ...

Inflammatory markers can indicate treatment efficacy and predict super-responder status in patients with psoriasis treated with biologics, according to one study. Blood count–derived inflammatory ...

Inflammation can feel like a localized fever, with redness, pain, heat and swelling. It’s how the body works to protect you after an injury, removing damaged tissue or invading bacteria and beginning ...

Chronic inflammation is both a driver and suppressor of cancer depending on context. Key players-NF-κB, IL-6, STAT3, TAMs, MDSCs, and Tregs-orchestrate a tumor-permissive microenvironment.

Severe alopecia areata is associated with elevated systemic inflammatory markers, which decrease with JAK inhibitor therapy, suggesting broader immune activation. The study identified higher levels of ...