Kyle Shanahan and Klay Kubiak are trying to reverse the script against a stingy Seahawks defense. Meanwhile, could Fred ...

The San Francisco 49ers will go into a vital Monday Night Football matchup vs. the Indianapolis Colts without two starters.

The San Francisco 49ers took on the Tennessee Titans on Sunday and earned a win, but there were a few 49ers who didn't have ...

On paper, that’s not the toughest ask, as the Colts have lost their last four games and have just a 12 percent chance of making the playoffs, according to ESPN. But in Week 15, Indianapolis added a ...

The San Francisco 49ers hosted the Tennessee Titans on Sunday at Levi's Stadium for an interconference battle in Week 15, and Kyle Shanahan's team went on to earn a 37-24 victory. Throughout the game, ...

The most recent move the San Francisco 49ers made involving Brandon Aiyuk suggested he may never suit up for this team again. After their Week 15 win, head coach Kyle Shanahan was asked what went into ...

The San Francisco 49ers beat the Tennessee Titans on Sunday, and in the locker room they celebrated their coach's birthday.

Kyle Shanahan recalled Trent Williams' stern message about his availability for Sunday's 49ers-Eagles wild-card game.