Scientists have re-created a pain pathway in the brain by growing four key clusters of human nerve cells in a dish. This laboratory model could be used to help explain certain pain syndromes, and ...

In a study published in Nature Human Behaviour on Oct. 9, researchers led by Profs. TU Yiheng and HU Li from the Institute of Psychology of the Chinese Academy of Sciences have uncovered a neural ...

A breakthrough discovery reveals how the SLC45A4 gene fine-tunes polyamine transport in sensory neurons, reshaping our understanding of pain and opening new paths for targeted therapies. Study: ...

Salk scientists uncover a key neural circuit in mice that gives pain its emotional punch, opening new doors for treating fibromyalgia, migraine, and PTSD LA JOLLA (July 9, 2025)—Pain isn’t just a ...

Pain serves as a warning system for actual or potential tissue damage but has a devastating impact when it lasts beyond its physiological role. Effective treatments for chronic pain remain a largely ...

Capsaicin, an active compound derived from chili peppers, has gained attention in clinical research for its ability to ...

Chronic pain is no joke. It can upend your life, steal away your ability to live in the moment and force you to find gumption within yourself you didn’t know existed. It’s something that an estimated ...

The cerebral cortex processes sensory information via a complex network of neural connections. How are these signals modulated to refine perception? A team from the University of Geneva (UNIGE) has ...

Researchers integrated four organoids that represent the four components of the human sensory pathway, along which pain signals are conveyed to the brain. Stimulation of the sensory organoid (top) by ...