Most pathogens use the external barriers of the airways, intestines, or genital tract as ports of entry, and the ability to mount an efficient mucosal immune response at these surfaces is critically ...

The cells that line the inside of the gut may play a key role in triggering inflammation that drives MS, a study found.

How does the gut cause Multiple Sclerosis? New research identifies the MHC II protein in intestinal epithelial cells as the trigger for MS-related neuroinflammation. Discover how gut-primed T cells ...

Multiple sclerosis (MS) is a debilitating neurological disorder caused by malfunctioning immune responses that target the ...

Biomarkers to predict immune-related adverse events with checkpoint inhibitors. This is an ASCO Meeting Abstract from the 2019 ASCO-SITC Clinical Immuno-Oncology Symposium. This abstract does not ...

In a recent article published in the European Journal of Internal Medicine, researchers in France indicated that T cell immune reaction correlates possibly with the chance of critical severe acute ...

Researchers suggest modulating intestinal microbiota or antigen-presenting activity of IECs represents new approaches to treating autoimmune neurological disease.

Introduction: Inflammation plays a pivotal role in blood pressure regulation. Data on experimental models of hypertension and hypertensive patients reflect the imbalance between T regulatory (Treg) ...

Scientists from the Icahn School of Medicine at Mount Sinai (MSSM) have published a study that describes the biological mechanism used by a family of proteins called histone deacetylases to activate ...

The cytokine profile (including key cytokine receptors as denoted by R), the effector cell type that is activated, and the corresponding types of infections are shown for each Th subgroup. The ...