Tragedy struck this week when a plane crashed in the city of Ahmedabad just shortly after takeoff, leaving investigators and aviation officials with many questions.

All but one of the 242 people on board the London-bound flight died when it crashed into a residential area in Ahmedabad shortly after take-off.

An Air India plane crashed into a medical college in Ahmedabad, killing people on the ground and leaving a sole survivor on the flight. Authorities said 269 died.

At the hospital in Ahmedabad, family members were giving DNA samples, waiting for official confirmation of their loss in the Air India disaster, and remembering their loved ones.

The Air India plane crash that led to the death of over 240 passengers on Thursday has plunged the airline into its biggest crisis yet and will pose a significant challenge to its efforts to revamp its reputation and fleet.

The pilot of the London-bound Air India jet that crashed Thursday put out an urgent call as the Boeing 787-8 quickly lost altitude on takeoff. “Mayday ... no thrust, losing power, unable to lift ,” Sumeet Sabharwal told traffic control less than a minute into the flight, per reports.

The governments of Canada and India are set to establish a new structure to share information about cross-border crimes, their latest step toward rebuilding ties nearly two years after Canadian officials accused India of orchestrating the murder of a Sikh activist near Vancouver.