Signaling is fundamental to how cells sense and respond to their environment—but in immune cells, those signals must be ...

Tooth root development relies on precise coordination of cellular signals, yet the underlying mechanisms remain unclear. Researchers have uncovered how two proteins, Gli2 and Gli3, work together to ...

Scientists led by Sergey Troyanovsky, Ph.D., professor of Dermatology and of Cell and Developmental Biology, have uncovered new intracellular mechanisms promoting cell-cell adhesion, a process ...

If we could listen to stem cells closely enough, we might hear them whisper, “mechanosenses tingling.” After all, stem cells sense and react to the physical forces around them, maintaining their ...

This proposed collection will examine how discoveries emerging from curiosity-driven research in cell and developmental biology have given rise to major ...

Cell signaling is crucial for cells to communicate and function correctly. Disruptions in these pathways, caused by genetic mutations or environmental factors, can lead to uncontrolled cell growth, ...

Macrophages, the immune system’s front-line scavenger cells, do more than simply digest dead cells. A new study published in ...

Study identifies impaired ER-to-golgi ceramide transport as a key regulatory node underlying senescence-associated sphingolipid remodeling.

(MEMPHIS, Tenn. – November 6, 2025) The enzyme RNA polymerase II transcribes genes into messenger RNA. This process is guided by modifications to the enzyme’s “tail” called phosphorylation patterns.