The abrupt cancellation of an independent Chinese film festival in New York reveals how Beijing and its proxies increasingly pressure critics abroad — a pattern documented by ICIJ and now drawing ...
ICP-488 is an oral, potent, and selective TYK2 allosteric inhibitor. By binding to the JH2 domain, ICP-488 blocks the signal transduction of IL-23, IL-12, type 1 IFN, and other inflammatory cytokines, ...