Houston basketball HC Kelvin Sampson shows respect Monday to Iowa State and T.J. Otzelberger after the Cougars’ 70-67 loss in Ames.

The top-10 Big 12 matchup features two of the conference's best teams, with Houston entering 23-2 and Iowa State at 22-3.

Second ranked UH basketball faces a stiff road test against Iowa State on Big Monday. Follow along for live updates.

Houston unraveled in the second half and allowed Iowa State to mount a furious comeback to steal the win on Monday.

SportsLine's model simulated the Houston Cougars vs. Iowa State Cyclones and revealed its Monday college basketball picks for this top-5 matchup

A potential Final Four matchup goes down Monday night in Ames, where the 6th-ranked Iowa State Cyclones will host the No. 2 Houston Cougars.

With the No. 166 tempo in the country, Iowa State is rarely the team speeding things up. Houston ranks 184 spots lower in pace. The teams have combined to go Under in 58% of their games this season, including the last three for ISU and five for the Cougars.

Get real-time Men's College Basketball coverage and scores as Houston Cougars takes on Iowa State Cyclones. We bring you the latest game previews, live stats, expert picks and recaps on CBS Sports