The San Francisco 49ers can't catch a break in their offensive backfield. It started in training camp when running back ...

Kyle Shanahan called running back Isaac Guerendo a long shot to play against the Dolphins earlier this week and he moved to ...

The other running backs on the 49ers' 53-man roster are Patrick Taylor Jr. and Israel Abanikanda. Taylor is expected to get ...

San Francisco 49ers running back Isaac Guerendo is unlikely to play in Sunday's game against the host Miami Dolphins, ESPN ...

The 49ers will have to start their fourth different running back this Sunday against the Miami Dolphins. That's because ...

Well this isn't good. 49ers rookie Isaac Guerendo is nursing a new injury. Kyle Shanahan revealed Guerendo was held out of ...

Curious to know about 49ers RB Isaac Guerendo‘s injury? The standout rookie has drawn attention for his breakout performances ...

The San Francisco 49ers face the Miami Dolphins this weekend and the rookie running back is now a major doubt to take part.

Guerendo (foot, hamstring) has been ruled out for Sunday's game at Miami, Matt Maiocco of NBC Sports Bay Area reports. Guerendo didn't practice this week and thus appears in danger of missing time ...

Isaac Guerendo faces an uphill climb if he wants to suit up on Sunday vs. the Dolphins after suffering a hamstring injury ...

San Francisco 49ers running back Isaac Guerendo appeared on Wednesday's injury report due to a hamstring issue sustained ...

ESPN insider Adam Schefter reported that San Francisco 49ers rookie running back Isaac Guerendo is unlikely to play against ...